Insert ear-probe assembly for high-quality otoacoustic-emission (OAE) measurements in adults Navy STTR FY2010.A Sol No.: Navy STTR FY2010.A Topic No.: N10A-T032 Topic Title: Insert ear-probe assembly for high-quality otoacoustic-emission (OAE) measurements in adults Proposal No.: N10A-032-0396 Firm: Etymotic Research, Inc. 61 Martin Lane Elk Grove Village, Illinois 60007 Contact: Jonathan Siegel Phone: (847) 491-2454 Web Site: www.etymotic.com Abstract: Current otoacoustic emission probes used for diagnostic evaluation of the middle and inner ear components of hearing can not produce well-calibrated, high-quality acoustic stimuli that cover the upper frequency range of human hearing that is most easily damaged by ototoxic drugs, noise and the normal process of aging. The microphones in these devices are also not calibrated to allow accurate presentation of acoustic stimuli or measure the acoustic emissions generated by the inner ear. Through a large-scale NIH-sponsored translational study at Northwestern University we have developed a prototype research-quality instrument that already satisfies nearly all of the specifications of the present call for proposals, but is also providing strong evidence that such measurements are likely to be of great diagnostic value. In partnership with Etymotic Research, Inc., we propose to create a practical and robust otoacoustic emission probe that satisfies the stated performance criteria. Although we already have a strong basis in experiments and theory to think about how to achieve this goal, we also understand how to thoroughly test components of the new probe, separately and in combination, to be able to propose a solution that will be virtually certain to work as specified. Benefits: Developing this probe would likely replace many of these devices used in research labs around the world and a large fraction of emission probe systems used in diagnostic otoacoustic emission systems in hearing clinics. The distinct advantage of designing a self-contained probe assembly follows Etymotic's approach of keeping the emission probe separate from the proprietary computer hardware and associated software in all commercial otoacoustic emission systems sold worldwide. This flexibility allows researchers to continue to develop the state of the art in emission measurement techniques and in elucidating the mechanisms of otoacoustic emissions. Better understanding of the science of emissions will continue to be translated into improved application in the clinic. Return