Miniature, Portable, Device to Detect and Monitor Coagulopathy Navy STTR FY2010.A Sol No.: Navy STTR FY2010.A Topic No.: N10A-T043 Topic Title: Miniature, Portable, Device to Detect and Monitor Coagulopathy Proposal No.: N10A-043-0347 Firm: Enterprise Sciences, Inc. 14817 Silverstone Drive Silver Spring, Maryland 20905-7429 Contact: Andrew Mostovych Phone: (301) 699-0097 Web Site: www.enterprisesciences.com Abstract: The objective of this proposal is to demonstrate the feasibility of a new thromboelastograph (TEG)-like instrument that has the same basic capabilities as the TEG - that is to say, capabilities of monitoring in vitro the kinetics, strength, and stability of clot formation in blood samples that are clot induced - but which is miniaturized, highly portable, rugged, and insensitive to adverse environmental conditions. Because current TEG devices use fundamental technology that is difficult to miniaturize and make robust, our approach will incorporate completely different technology and physical processes to measure comparable blood clotting parameters; it will furthermore provide various more advanced testing features. Benefits: Fulfillment of need in military segment for smaller, portable, ruggedized TEG-like device to detect coagulopathy in trauma cases and monitor effectiveness of replacement therapy. Lower cost of new device, along with enhanced capabilities, will expand the market to untapped commercial segments, thus improving medical care cost-effectively in a variety of medical establishments, notably small and medium sized hospitals, public and private clinics, and remote as well as mobile emergency care facilities. Return